WFU

2022年10月31日 星期一

Is Membrane Necessary in Bone Regeneration?


Ken-Chung CHEN
陳 畊仲


The conventional GTR procedure aims to achieve tissue regeneration, including bone, cementum, and connective tissue. Membrane application for epithelial cell occlusion and space maintenance are critical factors for GTR success. Along with the dental implant, bone augmentation in the edentulous site also develops essential. The concept of GBR was announced, similar to GTR, bone grafting, then reinforced membrane application for cell occlusion and space maintenance. But the environment of the edentulous site is different from the periodontal defect, and the dominant difference is that the periosteum is intact in the edentulous area. Is the cell occlusive membrane necessary in GBR? Does it isolate epithelial cells? Or osteoblast? Even blood supply from mucosa? These questions were emerging. In early 2000, titanium mesh with porosity was widely used in GBR and gained excellent results.

This procedure provides evidence that the hypothesis of cell occlusion in GBR is not crucial. In this topic, I will give evidence to discuss the membrane necessary in GBR.